Schema for D. grimshawi Net - D. grimshawi (Apr. 2014 (GEP/DgriImproved)) Alignment Net
  Database: dm3    Primary Table: netDgriImproved    Row Count: 105,704
fieldexampleSQL type info
bin 73smallint(5) unsigned range
level 1int(10) unsigned range
tName chr2Lvarchar(255) values
tStart 11215int(10) unsigned range
tEnd 152877int(10) unsigned range
strand -char(1) values
qName scaffold_15252varchar(255) values
qStart 17002063int(10) unsigned range
qEnd 17160374int(10) unsigned range
chainId 247int(10) unsigned range
ali 17520int(10) unsigned range
score 768052double range
qOver -1int(11) range
qFar -1int(11) range
qDup 0int(11) range
type topvarchar(255) values
tN 0int(11) range
qN 0int(11) range
tR 8441int(11) range
qR 7852int(11) range
tNewR -1int(11) range
qNewR -1int(11) range
tOldR -1int(11) range
qOldR -1int(11) range
tTrf 460int(11) range
qTrf 1544int(11) range

Sample Rows
 
binleveltNametStarttEndstrandqNameqStartqEndchainIdaliscoreqOverqFarqDuptypetNqNtRqRtNewRqNewRtOldRqOldRtTrfqTrf
731chr2L11215152877-scaffold_15252170020631716037424717520768052-1-10top0084417852-1-1-1-14601544
5852chr2L1152111770-scaffold_152521715971617160066000-1-1-1gap0000-1-1-1-100
5852chr2L1192312077-scaffold_152521715940617159563000-1-1-1gap0000-1-1-1-100
5852chr2L1293413517-scaffold_152521715849217158542000-1-1-1gap0000-1-1-1-100
5852chr2L1409814127-scaffold_152521715788017157912000-1-1-1gap0000-1-1-1-100
5852chr2L1488314935-scaffold_152521715708317157130000-1-1-1gap0000-1-1-1-100
5852chr2L1571817050-scaffold_152521715414717156300000-1-1-1gap00900-1-1-1-100
5852chr2L17141104471-scaffold_152521705892617154056000-1-1-1gap0075603785-1-1-1-1394867
5853chr2L2212224965+scaffold_1520311318992113217511453223491697-1-10nonSyn0024998-1-1-1-100
5854chr2L2268922737+scaffold_152031131956211319628000-1-1-1gap0000-1-1-1-100

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

D. grimshawi Net (netDgriImproved) Track Description
 

Description

This track shows the best D. grimshawi/D. melanogaster chain for every part of the D. melanogaster genome. It is useful for finding orthologous regions and for studying genome rearrangement. The D. grimshawi sequence used in this annotation is from the Apr. 2014 (GEP/DgriImproved) (DgriImproved) assembly.

Display Conventions and Configuration

In full display mode, the top-level (level 1) chains are the largest, highest-scoring chains that span this region. In many cases gaps exist in the top-level chain. When possible, these are filled in by other chains that are displayed at level 2. The gaps in level 2 chains may be filled by level 3 chains and so forth.

In the graphical display, the boxes represent ungapped alignments; the lines represent gaps. Click on a box to view detailed information about the chain as a whole; click on a line to display information about the gap. The detailed information is useful in determining the cause of the gap or, for lower level chains, the genomic rearrangement.

Individual items in the display are categorized as one of four types (other than gap):

  • Top - the best, longest match. Displayed on level 1.
  • Syn - line-ups on the same chromosome as the gap in the level above it.
  • Inv - a line-up on the same chromosome as the gap above it, but in the opposite orientation.
  • NonSyn - a match to a chromosome different from the gap in the level above.

Methods

Chains were derived from blastz alignments, using the methods described on the chain tracks description pages, and sorted with the highest-scoring chains in the genome ranked first. The program chainNet was then used to place the chains one at a time, trimming them as necessary to fit into sections not already covered by a higher-scoring chain. During this process, a natural hierarchy emerged in which a chain that filled a gap in a higher-scoring chain was placed underneath that chain. The program netSyntenic was used to fill in information about the relationship between higher- and lower-level chains, such as whether a lower-level chain was syntenic or inverted relative to the higher-level chain. The program netClass was then used to fill in how much of the gaps and chains contained Ns (sequencing gaps) in one or both species and how much was filled with transposons inserted before and after the two organisms diverged.

Credits

The chainNet, netSyntenic, and netClass programs were developed at the University of California Santa Cruz by Jim Kent.

Blastz was developed at Pennsylvania State University by Minmei Hou, Scott Schwartz, Zheng Zhang, and Webb Miller with advice from Ross Hardison.

Lineage-specific repeats were identified by Arian Smit and his program RepeatMasker.

The browser display and database storage of the nets were made by Robert Baertsch and Jim Kent.

References

Kent, W.J., Baertsch, R., Hinrichs, A., Miller, W., and Haussler, D. Evolution's cauldron: Duplication, deletion, and rearrangement in the mouse and human genomes. Proc Natl Acad Sci USA 100(20), 11484-11489 (2003).

Schwartz, S., Kent, W.J., Smit, A., Zhang, Z., Baertsch, R., Hardison, R., Haussler, D., and Miller, W. Human-Mouse Alignments with BLASTZ. Genome Res. 13(1), 103-7 (2003).