These tracks show the putative housekeeping (hkCP) and developmental (dCP) enhancers identified by STARR-Seq in S2 and OSC cells. The regions that are enriched in STARR-Seq reads were identified by MACS2. The log likelihood ratio evidence tracks were also produced by MACS2.
The STARR-Seq reporters used in this study are as follows:
|RpS12 (hkCP)||Ribosomal protein gene 12||Housekeeping|
|eEF1delta||Eukaryotic translation elongation factor 1 delta||Housekeeping|
|NipB||Cohesin loader Nipped-B||Housekeeping|
|X16||Putative splicing factor x16||Housekeeping|
|DSCP (dCP)||Derived from the even-skipped transcription factor||Developmental|
|pnr||Derived from the pannier transcription factor||Developmental|
Zabidi MA, Arnold CD, Schernhuber K, Pagani M, Rath M, Frank O, Stark A. Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation. Nature. 2015 Feb 26;518(7540):556-9.
Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137.