Schema for Inhibit Topoisomerases PolII ChIP-Seq - PolII ChIP-Seq After Inhibition of Topoisomerases
  Database: dm6    Primary Table: GSE47795_PolII_Camp_macs    Row Count: 37,445   Data last updated: 2022-10-20
fieldexampleSQL type info
bin 585smallint(5) unsigned range
chrom chr2Lvarchar(255) values
chromStart 6575int(10) unsigned range
chromEnd 6796int(10) unsigned range
name GSE47795_PolII_Camp_macs_pe...varchar(255) values
score 31int(10) unsigned range
strand .char(1) values
signalValue 1.82493float range
pValue 4.69735float range
qValue 3.18143float range
peak 147int(11) range

Sample Rows
 
binchromchromStartchromEndnamescorestrandsignalValuepValueqValuepeak
585chr2L65756796GSE47795_PolII_Camp_macs_peak_131.1.824934.697353.18143147
585chr2L72767662GSE47795_PolII_Camp_macs_peak_231.1.824934.697353.18143104
585chr2L1189612161GSE47795_PolII_Camp_macs_peak_326.1.637994.059932.6582855
585chr2L1302313183GSE47795_PolII_Camp_macs_peak_4117.2.4784414.119711.764274
585chr2L1453614689GSE47795_PolII_Camp_macs_peak_558.2.05877.753055.8400186
585chr2L1507015305GSE47795_PolII_Camp_macs_peak_654.2.03937.322975.45448172
585chr2L4599047439GSE47795_PolII_Camp_macs_peak_7a122.2.7118114.657312.278175
585chr2L4599047439GSE47795_PolII_Camp_macs_peak_7b111.2.6500613.501411.1774478
585chr2L4599047439GSE47795_PolII_Camp_macs_peak_7c100.2.5619212.326410.0611636
585chr2L4599047439GSE47795_PolII_Camp_macs_peak_7d188.3.2287221.473618.8629880

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

Inhibit Topoisomerases PolII ChIP-Seq (GSE47795_polII_chipseq) Track Description
 

Description

These tracks show the regions in the D. melanogaster genome that are significantly enriched in RNA Polymerase II (PolII) in S2 cells as determined by MACS2. The samples were treated with Camptothecin to inhibit topoisomerase I (Top1), and treated with ICRF-193 to inhibit topoisomerase II (Top2). The Irreproducible Discovery Rate (IDR) peak calls were produced by the idr program using a global IDR threshold of 0.05.

The PolII ChIP-Seq datasets were obtained from the NCBI Gene Expression Omnibus database under the accession number GSE47795.

References

Teves SS, Henikoff S. Transcription-generated torsional stress destabilizes nucleosomes. Nat Struct Mol Biol. 2014 Jan;21(1):88-94.

Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137. doi: 10.1186/gb-2008-9-9-r137. Epub 2008 Sep 17.