Schema for Inhibit Topoisomerases PolII ChIP-Seq - PolII ChIP-Seq After Inhibition of Topoisomerases
  Database: dm6    Primary Table: GSE47795_PolII_Control_macs    Row Count: 7,075   Data last updated: 2022-10-20
fieldexampleSQL type info
bin 585smallint(5) unsigned range
chrom chr2Lvarchar(255) values
chromStart 14571int(10) unsigned range
chromEnd 14718int(10) unsigned range
name GSE47795_PolII_Control_macs...varchar(255) values
score 32int(10) unsigned range
strand .char(1) values
signalValue 2.2857float range
pValue 5.56457float range
qValue 3.24683float range
peak 61int(11) range

Sample Rows
 
binchromchromStartchromEndnamescorestrandsignalValuepValueqValuepeak
585chr2L1457114718GSE47795_PolII_Control_macs_peak_132.2.28575.564573.2468361
585chr2L4599046231GSE47795_PolII_Control_macs_peak_2a31.2.346555.450553.155949
585chr2L4599046231GSE47795_PolII_Control_macs_peak_2b53.2.786538.176495.33925214
585chr2L4678247446GSE47795_PolII_Control_macs_peak_3a71.3.0798510.21737.1023297
585chr2L4678247446GSE47795_PolII_Control_macs_peak_3b96.3.446512.99199.63086312
585chr2L5265753331GSE47795_PolII_Control_macs_peak_4a80.3.2265111.29868.07595255
585chr2L5265753331GSE47795_PolII_Control_macs_peak_4b85.3.2998411.85388.58279467
585chr2L6248962656GSE47795_PolII_Control_macs_peak_520.1.986583.901942.0396122
585chr2L6849168673GSE47795_PolII_Control_macs_peak_633.2.298045.738283.3849798
585chr2L7642576588GSE47795_PolII_Control_macs_peak_727.2.089194.900152.7610240

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

Inhibit Topoisomerases PolII ChIP-Seq (GSE47795_polII_chipseq) Track Description
 

Description

These tracks show the regions in the D. melanogaster genome that are significantly enriched in RNA Polymerase II (PolII) in S2 cells as determined by MACS2. The samples were treated with Camptothecin to inhibit topoisomerase I (Top1), and treated with ICRF-193 to inhibit topoisomerase II (Top2). The Irreproducible Discovery Rate (IDR) peak calls were produced by the idr program using a global IDR threshold of 0.05.

The PolII ChIP-Seq datasets were obtained from the NCBI Gene Expression Omnibus database under the accession number GSE47795.

References

Teves SS, Henikoff S. Transcription-generated torsional stress destabilizes nucleosomes. Nat Struct Mol Biol. 2014 Jan;21(1):88-94.

Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137. doi: 10.1186/gb-2008-9-9-r137. Epub 2008 Sep 17.