Schema for Inhibit Topoisomerases PolII ChIP-Seq - PolII ChIP-Seq After Inhibition of Topoisomerases
  Database: dm6    Primary Table: GSE47795_PolII_ICRF_macs    Row Count: 36,852   Data last updated: 2022-10-20
fieldexampleSQL type info
bin 585smallint(5) unsigned range
chrom chr2Lvarchar(255) values
chromStart 8082int(10) unsigned range
chromEnd 8372int(10) unsigned range
name GSE47795_PolII_ICRF_macs_pe...varchar(255) values
score 67int(10) unsigned range
strand .char(1) values
signalValue 2.22511float range
pValue 8.76258float range
qValue 6.71388float range
peak 203int(11) range

Sample Rows
 
binchromchromStartchromEndnamescorestrandsignalValuepValueqValuepeak
585chr2L80828372GSE47795_PolII_ICRF_macs_peak_167.2.225118.762586.71388203
585chr2L1438314712GSE47795_PolII_ICRF_macs_peak_2a43.1.908466.147344.3995761
585chr2L1438314712GSE47795_PolII_ICRF_macs_peak_2b123.2.6107714.836412.3712222
585chr2L1520015610GSE47795_PolII_ICRF_macs_peak_344.1.923216.181114.429455
585chr2L2188122018GSE47795_PolII_ICRF_macs_peak_499.2.5683412.23149.9079674
585chr2L2272823032GSE47795_PolII_ICRF_macs_peak_521.1.676553.50662.19311221
585chr2L3231732493GSE47795_PolII_ICRF_macs_peak_625.1.628373.989732.5922443
585chr2L3377433946GSE47795_PolII_ICRF_macs_peak_726.1.639144.020252.6182496
585chr2L3724437393GSE47795_PolII_ICRF_macs_peak_852.1.957577.17635.2967175
585chr2L4599747442GSE47795_PolII_ICRF_macs_peak_9a164.3.056519.112516.4691187

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

Inhibit Topoisomerases PolII ChIP-Seq (GSE47795_polII_chipseq) Track Description
 

Description

These tracks show the regions in the D. melanogaster genome that are significantly enriched in RNA Polymerase II (PolII) in S2 cells as determined by MACS2. The samples were treated with Camptothecin to inhibit topoisomerase I (Top1), and treated with ICRF-193 to inhibit topoisomerase II (Top2). The Irreproducible Discovery Rate (IDR) peak calls were produced by the idr program using a global IDR threshold of 0.05.

The PolII ChIP-Seq datasets were obtained from the NCBI Gene Expression Omnibus database under the accession number GSE47795.

References

Teves SS, Henikoff S. Transcription-generated torsional stress destabilizes nucleosomes. Nat Struct Mol Biol. 2014 Jan;21(1):88-94.

Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137. doi: 10.1186/gb-2008-9-9-r137. Epub 2008 Sep 17.