Schema for Basal Transcription Factors ChIP-exo - ChIP-exo of Basal Transcription Factors in S2R+ Cells
  Database: dm6    Primary Table: gfzf_Baumann2018_macs    Row Count: 1,981   Data last updated: 2022-10-21
fieldexampleSQL type info
bin 585smallint(5) unsigned range
chrom chr2Lvarchar(255) values
chromStart 18582int(10) unsigned range
chromEnd 18721int(10) unsigned range
name GFZF_Baumann2018_macs_peak_1varchar(255) values
score 968int(10) unsigned range
strand .char(1) values
signalValue 40.0258float range
pValue 100.932float range
qValue 96.8443float range
peak 73int(11) range

Sample Rows
 
binchromchromStartchromEndnamescorestrandsignalValuepValueqValuepeak
585chr2L1858218721GFZF_Baumann2018_macs_peak_1968.40.0258100.93296.844373
585chr2L2138721526GFZF_Baumann2018_macs_peak_21194.23.5443123.88119.44958
586chr2L156056156199GFZF_Baumann2018_macs_peak_3170.10.798920.122517.046292
586chr2L158869159056GFZF_Baumann2018_macs_peak_4203.12.794323.521620.375793
586chr2L252340252480GFZF_Baumann2018_macs_peak_5203.12.794323.521620.375771
587chr2L285735285845GFZF_Baumann2018_macs_peak_663.6.472739.234036.3686760
587chr2L305675305980GFZF_Baumann2018_macs_peak_7a61.6.299398.93336.1048843
587chr2L305675305980GFZF_Baumann2018_macs_peak_7b291.16.71132.405929.1555218
588chr2L414719415159GFZF_Baumann2018_macs_peak_8a453.22.519848.8345.373778
588chr2L414719415159GFZF_Baumann2018_macs_peak_8b116.9.3903814.60111.6138338

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

Basal Transcription Factors ChIP-exo (TFChIPexo) Track Description
 

Description

These tracks show the results of the ChIP-exo analyses of the transcription factors that are associated with the core promoters in S2R+ cells, including the Motif 1 Binding Protein (M1BP) and the GST-containing FLYWCH zinc-finger protein (gfzf). To increase the gfzf signal, an additional gfzf sample was crosslinked with dimethyl adipimidate and ethylene glycol bis(succinimidyl succinate), and then with formaldehyde (gfzf_3xlink).

The regions that are enriched in the transcription factors were identified by MACS2, Peakzilla, PeakXus. The log likelihood ratio evidence tracks were produced by MACS2.

The ChIP-exo datasets were obtained from the Gene Expression Omnibus database at NCBI under the accession numbers GSE97841 and GSE105009.

References

Baumann DG, Dai MS, Lu H, Gilmour DS. GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional co-activator. Mol Cell Biol. 2018. Mol Cell Biol 38:e00476-17.

Baumann DG, Gilmour DS. A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes. Nucleic Acids Res. 2017 Oct 13;45(18):10481-10491.

Bardet AF, Steinmann J, Bafna S, Knoblich JA, Zeitlinger J, Stark A. Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics. 2013 Nov 1;29(21):2705-13.

Hartonen T, Sahu B, Dave K, Kivioja T, Taipale J. PeakXus: comprehensive transcription factor binding site discovery from ChIP-Nexus and ChIP-Exo experiments. Bioinformatics. 2016 Sep 1;32(17):i629-i638.

Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137.