Schema for Pfam in RefSeq - Pfam Domains in RefSeq Genes
  Database: dm6    Primary Table: pfam_refseq_genes    Row Count: 25,865   Data last updated: 2022-10-21
fieldexampleSQL type info
bin 585smallint(5) unsigned range
chrom chr2Lvarchar(255) values
chromStart 8730int(10) unsigned range
chromEnd 9258int(10) unsigned range
name Peptidase_C48varchar(255) values
score 0int(10) unsigned range
strand +char(1) values
thickStart 0int(10) unsigned range
thickEnd 0int(10) unsigned range
reserved 0int(10) unsigned range
blockCount 1int(10) unsigned range
blockSizes 528,longblob  
chromStarts 0,longblob  

Sample Rows

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

Pfam in RefSeq (pfam_refseq_genes) Track Description


Most proteins are composed of one or more conserved functional regions called domains. This track shows the high-quality, manually-curated Pfam-A domains found in proteins associated with the RefSeq Genes transcripts.


The proteins associated with RefSeq genes were submitted to the set of Pfam-A HMMs which annotate regions within the predicted peptide that are recognizable as Pfam protein domains. These regions are then mapped to the transcripts themselves using the pslMap utility.

Of the several options for filtering out false positives, the "Trusted cutoff (TC)" threshold method is used in this track to determine significance. For more information regarding thresholds and scores, see the HMMER documentation and results interpretation pages.

Note: There is currently an undocumented but known HMMER problem which results in lessened sensitivity and possible missed searches for some zinc finger domains. Until a fix is released for HMMER /PFAM thresholds, please also consult the "UniProt Domains" subtrack of the UniProt track for more comprehensive zinc finger annotations.


pslMap was written by Mark Diekhans at UCSC.


Finn RD, Coggill P, Eberhardt RY, Eddy SR, Mistry J, Mitchell AL, Potter SC, Punta M, Qureshi M, Sangrador-Vegas A, Salazar GA, Tate J, Bateman A. The Pfam protein families database: towards a more sustainable future. Nucleic Acids Res. 2016 Jan 4;44(D1):D279-85.